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1. Renin-angiotensin system polymorphisms and risk of hypertension ...
Renin-angiotensin system (RAS) polymorphisms have been studied as candidate risk factors for hypertension with inconsistent results, possibly due to heterogeneity among various environmental factors. We analyzed the association between ...

2. Obesity and the lung: 5 {middle dot} Obesity and COPD -- Franssen ...
... resistin, adipsin, leptin, acylation stimulating protein (ASP), plasminogen activator inhibitor-1 (PAI-1), lipoprotein lipase (LPL) and components of the renin-angiotensin system76—which may exert local and systemic effects. ...

3. Aliskiren Accumulates in Renin Secretory Granules and Binds Plasma ...
30% of prorenin was detected in renin-specific assays. In conclusion, aliskiren accumulates in renin granules, thus allowing long-lasting renin-angiotensin system blockade beyond the half-life of this drug. Aliskiren also binds to ...

4. [Scientific Contribution] Aliskiren Accumulates in Renin Secretory ...
Abstract—The vascular effects of aliskiren last longer than expected based on its half life, and this renin inhibitor has been reported to cause a greater renin rise than other renin-angiotensin system blockers. ...

5. cfs as energy metabolism dysregulation
a range of indirect evidence suggests that the renin-angiotensin system stimulates mitochondrial responsiveness and reduces mitochondrial efficiency: chronic under-stimulation of this system could contribute to cfs aetiology. ...

6. Changes in Kidney Function Following Heart Failure Treatment ...
... that block the renin-angiotensin system (RAS). The discussion then builds upon the basic pathophysiology concepts introduced earlier in this issue to explain how therapies commonly used in heart failure affect kidney function. ...

7. Medical eBooks
Namely, renal blood pressure regulation seems to be involved in five major pathophysiological mechanisms (all closely related to the renin-angiotensin system): Pressure-natriuresis, renal sympathetic nervous system, renal blood flow, ...

8. New research in Hypertension Control
... with 18241 participants), CCBs (4 trials with 44825 participants), or ACE inhibitors or ARBs, which were grouped together as renin-angiotensin system (RAS) inhibitors because of small numbers (3 trials with 10828 participants). ...

9. New and old markers of progression of diabetic nephropathy ...
In type 2 diabetes, the non-albuminuric pathway may explain a decline in GFR to <60ml/min/1.73m2 in approximately one in four subjects after accounting for the use of renin angiotensin system inhibitors. ...

10. entry for july 09, 2008 hypertension (high blood pressure) part one
low-renin hypertension is more common in african americans than white americans, and may explain why african americans tend to respond better to diuretic therapy than drugs that interfere with the renin-angiotensin system. ...